Unique method

It is currently difficult to determine with certainty whether rectal cancer has spread to nearby lymph nodes outside the intestine. It is only after the operation (when the resected tissue has been examined) that any spread can be determined.

NanoEcho’s imaging system, which is based on magnetomotive ultrasound, is designed to identify the possible spread of rectal cancer to nearby lymph nodes prior to surgery. The aim is to provide the medical team with information so that they can offer a more individualised treatment.

NanoEcho’s innovative patented method is based on nanotechnology combined with modern ultrasound technology. A magnetic field together with iron oxide-based nanoparticles is combined with diagnostic ultrasound in a completely new way.

How the method works

  • Iron oxide based nanoparticles are injected and used as contrast agent
  • By applying a magnetic field, the nanoparticles are set in motion
  • Ultrasound diagnostics are used to image the movement
  • The amount of accumulated nanoparticles allows differentiation between healthy and diseased tissues

This is how we intend to do it at the clinic

Iron oxide based nanoparticles are injected via the intestine and used as contrast agent

The amount of accumulated nanoparticles allows differentiation between healthy and diseased tissues.

By applying a magnetic field, the nanoparticles are set in motion. Ultrasound diagnostics are used to image the movement.

The NanoTrace® imaging signal is then displayed on the screen.

Patent

NanoEcho pursues an active patent strategy, whereby the patent portfolio is continuously evaluated to be at the forefront as well as in line with the operational activities. The company has a basic patent that protects the performance of a hand-held probe. The patent covers the unique combination of placing an ultrasonic sensor together with one or more magnets in or on the same unit. This basic patent has been granted in Japan, Europe, and South Korea and is under review in Canada and the US, where the process is proceeding according to plan. In addition to this patent, NanoEcho has applied for a more detailed patent in the US, Japan, China, Canada, and Europe regarding the design and construction of the probe. The focus of this patent is on optimising the sensitivity of the equipment. The company has implemented a Freedom To Operate (FTO), which has shown that there are no patent obstacles to the technology.

We have a strong patent protection for a hand-held probe that uses the technology of magnetomotive ultrasound

Advantages of the technology

Better resolution of the images than with a magnetic camera investigation

Clear boundary between diseased and healthy tissue

Portable and easy to use

Can be used at the
hospital bed

NanoEcho’s innovative method, with its high precision, aims to facilitate the differentiation between diseased and healthy tissue and at the same time determine a more precise localization of cancerous tissue. The goal is to be able to provide a more precise, simpler and more cost-effective diagnosis of, among other things, cancer diseases.

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NanoEcho AB
Gasverksgatan 1
222 29 Lund
info@nanoecho.se

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